After SMILE Pro, the small bag of eye drops you go home with does more heavy lifting for your recovery than almost anything else. Used correctly, they prevent infection, calm inflammation, and keep your eyes comfortable while they heal. Skip them or use them wrong, and you give avoidable problems a foothold at the worst possible moment.
So it’s worth understanding exactly what each bottle is for, how long you’ll need it, and how to put the drops in properly. This guide from Visual Aids Centre breaks down the three main types of drops after SMILE Pro, a typical schedule, the correct technique, and the everyday mistakes that are easy to avoid once you know them.
Key Takeaways
- You’ll usually be prescribed three kinds of drops after SMILE Pro: an antibiotic, an anti-inflammatory (steroid), and lubricating drops.
- Antibiotic and steroid drops run for a set short course; lubricating drops continue longer and can be used freely for comfort.
- Use drops in the right order, wait about 5 minutes between different types, and never let the bottle tip touch your eye.
- Don’t stop the medicated drops early just because your eyes feel fine — the schedule is timed to healing, not symptoms.
- More lubricating drops are fine, but overusing certain other drops isn’t — follow your surgeon’s instructions exactly.
Why Eye Drops Are So Important After SMILE Pro
SMILE Pro is a minimally invasive, flapless procedure, but the surface of your eye still needs support while it seals and settles in the first weeks. That’s the job of your drops. The medicated ones protect against the two things most likely to interfere with a clean recovery — infection and excess inflammation — while lubricating drops keep the surface moist and comfortable through the temporary dryness that follows any laser correction.
This is why the drop schedule isn’t a loose suggestion. Each bottle targets a specific part of the healing process, and the timing is built around how your eye recovers day by day. Treat the drops as the core of your aftercare, not an optional extra.
The Three Types of Drops You’ll Use
Most SMILE Pro patients go home with three distinct bottles, each doing a different job. Knowing which is which prevents mix-ups.
Antibiotic Drops
These guard against infection while the surface heals and are usually prescribed for a short, defined course in the first week or so. Because infection is the most serious early risk, finishing the full course matters even if your eyes feel perfectly fine — the timeline is covered in how long to use antibiotic eye drops.
Anti-Inflammatory (Steroid) Drops
Steroid drops calm the natural inflammation that follows surgery, supporting a smooth, even recovery. These are typically tapered — reduced gradually rather than stopped abruptly — over a couple of weeks, and they must be used exactly as directed, as explained in how long to use steroid drops. A common version is prednisolone, covered in our note on prednisolone drops after surgery.
Lubricating Drops (Artificial Tears)
These ease dryness and grittiness and are the most flexible of the three — you can generally use them as often as you need for comfort, often well beyond the medicated course. Their typical timeline is set out in how long to use artificial tears.
A Typical Eye Drop Schedule
Every clinic’s regimen differs slightly, so this is an illustration rather than your prescription — your surgeon’s exact instructions always take precedence. A common pattern looks something like this:
- Antibiotic drops: several times a day for roughly the first week.
- Steroid drops: several times a day initially, then tapered down over about two weeks.
- Lubricating drops: every few hours as needed, continuing for several weeks or longer.
If you’re prescribed more than one medicated drop, you don’t put them in together. Leave a gap of around five minutes between different types so each is properly absorbed rather than washed out by the next. For the bigger picture of how these fit into the full recovery, see what kind of eye drops you need after surgery.
How to Put in Eye Drops Correctly
Good technique makes the drops more effective and keeps things hygienic. Here’s a simple, reliable method:
- Wash your hands thoroughly before you start.
- Tilt your head back and look up toward the ceiling.
- Pull down your lower lid gently with one finger to form a small pocket.
- Squeeze one drop into that pocket — one is enough; the eye can’t hold more.
- Don’t let the tip touch your eye, lashes, or fingers, which would contaminate the bottle.
- Close your eye for a minute and press lightly on the inner corner to help the drop stay on the eye rather than draining away.
If your lashes feel sticky or crusted in the mornings during healing, clean them gently first, so the drops reach the surface cleanly.
Common Mistakes to Avoid
A few easy slip-ups can blunt the benefit of your drops or cause irritation. Steer clear of these:
- Stopping medicated drops early. Feeling fine isn’t the same as being fully healed — finish the antibiotic course and taper the steroid exactly as instructed.
- Doubling up to “catch up”. Two drops don’t work better than one, and overusing certain drops can backfire, as our guide on whether you can use too many eye drops after surgery explains.
- Putting different drops in back-to-back. Skipping the five-minute gap washes the first drop away.
- Using leftover or non-prescribed drops. Over-the-counter redness relievers, for instance, aren’t a substitute for what your surgeon prescribed.
- Forgetting the night shield. Drops protect the surface, but the shield stops unconscious rubbing.
Lubricating Drops and Long-Term Comfort
Once your medicated courses finish, lubricating drops often stay in your routine for a while longer, and that’s completely normal. Temporary dryness is part of recovery from any corneal laser procedure, and good artificial tears keep your eyes comfortable while tear production returns to its usual level. Many patients find a quality preservative-free lubricant the single most useful thing in the weeks after surgery — our rundown of the best lubricating drops after surgery covers what to look for.
If dryness feels more stubborn than expected, it’s worth understanding and managing rather than just enduring.
Conclusion
Your eye drops are the engine of a smooth SMILE Pro recovery. Expect three kinds — antibiotic to prevent infection, steroid to control inflammation, and lubricating drops for comfort — each with its own purpose and timeline. Use them in order with a gap between types, put them in with clean hands and good technique, finish the medicated courses even when your eyes feel great, and lean on lubricating drops for as long as you need them. Get those basics right and you remove most of the avoidable bumps from your recovery.
Unsure about your specific drops or schedule? Don’t guess. Contact Visual Aids Centre and we’ll walk you through your regimen step by step, so you can heal with confidence.
Frequently Asked Questions (FAQs)
What eye drops do I need after SMILE Pro?
Usually three: an antibiotic to prevent infection, an anti-inflammatory (steroid) to control swelling, and lubricating drops for comfort. Your surgeon will prescribe the exact ones and schedule.
How long do I use eye drops after SMILE Pro?
Antibiotic drops typically run about a week, steroid drops are tapered over roughly two weeks, and lubricating drops can continue for several weeks or longer as needed for comfort.
Can I use too many eye drops after SMILE Pro?
Lubricating drops can be used freely, but medicated drops must follow the prescribed dose — overusing them can cause problems. Never double up to make up for a missed dose.
What if I forget a dose of my drops?
Take it as soon as you remember, then continue as normal — don’t put in two doses at once. If you miss several, contact your surgeon for advice rather than guessing.
Can I stop my drops once my eyes feel fine?
No. Feeling fine isn’t the same as being healed. Finish the antibiotic course and taper the steroid exactly as directed; stopping early can let infection or inflammation take hold.
How long should I wait between different eye drops?
About five minutes. Putting different drops in back-to-back washes the first one away before it’s absorbed, reducing its effect.
👁️ MEDICALLY REVIEWED BY
Padmashree Dr. Vipin Buckshey
Optometrist & Post-Operative Care Specialist | AIIMS Graduate, 1977 | Padma Shri Honouree | Refractive Surgery Specialist, Visual Aids Centre
If there is one piece of aftercare Dr. Vipin Buckshey reinforces most firmly at Visual Aids Centre, it is the eye drop routine. In four decades of refractive practice he has seen that the patients who follow the schedule faithfully — finishing the antibiotic, tapering the steroid, using lubricants for comfort — are the ones whose recoveries are smoothest and most predictable. His emphasis is always on understanding why each drop matters, because patients who grasp the purpose are far more likely to use them correctly than those handed a list without explanation. The guidance in this article reflects exactly the counselling his SMILE Pro patients receive before discharge. An AIIMS alumnus, Padma Shri honouree, and former President of the Indian Optometric Association, Dr. Buckshey is known for aftercare advice that is clear, practical, and easy to follow. Read more on our story.





